New Method for Injectable Quinine Quality Assurance Control Using a Multi-Spectral Microscope

arXiv:2510.02421v1 Announce Type: new
Abstract: Africa is the world region that is most affected by malaria. Among the thera- pies used, injectable quinine is considered to be one of the effective antima- larial drug, however non-quality assured antimalarials clearly have a strong market penetration across Africa. To overcome this problem, it becomes more and more necessary to set up quantitative and qualitative analysis system for antimalarial quality control. The objective of the present investigation is an attempt to use customized multispectral microscope equipped with UV-Visible lasers for injectable quinine quality assurance control routinely. For that, we have established the calibration curve of quinine solution concentration as a function of area under light intensity histogram crossing the solution. From this calibration curve, we can check the conformity of any injectable quinine according to the pharmacopoeia involved. The proposed technique is a prom- ising alternative for drug quality control routinely.