arXiv:2512.08014v1 Announce Type: new
Abstract: Purpose: HDR brachytherapy is a widely adopted modality for cancer treatment. However, it is not free from error and uncertainty. In-vivo dosimetry (IVD) is the only technique that can confirm correct dose delivery. This study details and validates a calibration method for Plastic Scintillation Detector (PSD), bypassing dose gradient and positioning issues in brachytherapy calibration. Methods: The PRB-0057 PSD (Medscint, Canada) was calibrated, 1×1 mm scintillating fiber coupled to a 20 m Eska GH-4001 clear optical fiber (Mitsubishi Rayon, Japan). The fiber is connected to the Hyperscint-RP200 research platform for signal collection. Hyperspectral calibration was performed at a LINAC with a 6 MV beam, enabling removal of stem effects before brachytherapy measurements. For validation, an Iridium-192 Flexisource (Elekta Brachy, The Netherlands), Sk=29447U, was used in a motorized IBA-Blue-Phantom2 water tank (48x48x41cm3). Dose rates were measured at 10 Hz along the source z-axis at a fixed transverse distance of 1.2+/-0.05 cm in 0.2 cm steps. Relative difference (RD) between measured and TG-43U1 dose rates was assessed. A detailed uncertainty budget was associated with brachytherapy measurements. Results: Comparison shows good agreement with RD around 2.5 $%$ at 1.2 cm, corresponding to positional uncertainties of